Endocrine Disruptors
An endocrine disruptor is an exogenous substance or mixture that alters function(s) of the endocrine system and consequently causes adverse health effects in an intact organism, or its progeny, or (sub)populations (EC).
Endocrine disrupting chemicals are mostly man-made substances that can mimic or interfere with the function of hormones in the body. Endocrine disruptors can interfere i.e. turn on, turn off, or modify hormone-transmitting signals that can affect normal tissue and organ functions. Many of these substances have been associated with developmental, reproductive, neural, immune and other problems animals or men... Read more...
InterBioTox is prepared to support you in testing your substance on endocrine disrupting properties with the following studies/services:
InterBioTox fully supports selected ecotoxicology and in vivo toxicology studies within a safety assessment of endocrine disruptors using a comprehensive GLP analytical services. Choose the study...
InterBioTox offers the aquatic, sediment and terrestrial ecotoxicology studies on endocrine disruptors for the environmental safety assessment within Level 4 of the Conceptual Framework in GLP quality (the offered studies are OECD 234, 218, 219, 211, 222 and 225). Choose the study...
InterBioTox provides an in vitro assay in GLP quality on Estrogen or androgen receptor binding affinity (YES/YAS Assay) within Level 2 of the OECD Conceptual Framework. Choose the study...
Mammalian in vivo toxicology studies on endocrine disruptors play an important part within safety assessment of these products. InterBioTox supports the clients with the GLP studies in Level 4 of the OECD Conceptual Framework: sub-acute (OECD 407), sub-chronic & chronic (OECD 408 and 453), and reproductive & developmental toxicology studies (OECD 414, 416, 421 and 422). Choose the study...
InterBioTox fully supports the in vivo toxicology studies within Level 4 of the OECD Conceptual Framework by conduct of histopathology as a requisite part of the mammalian toxicology studies and fully pursuant to the latest guideline. Choose the study...
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