These tests measure physical and chemical properties of substances. They are requisite together with toxicological and ecotoxicological properties for a reliable safety assessment of various chemical substances, pesticides, biocides etc. to human health and the environment, to help predicting toxicological or environmental hazards and behaviour.
The Physico-chemical testing represents an integral part of the standard information requirements and are necessary for the registration of chemical substances, pesticides, biocides etc....Read more...
The OECD (Organisation for Economic Cooperation and Development) has developed standardized testing methods as a part of the registration of chemicals which are internationally accepted.
We provide test data for physicochemical properties including melting temperature, boiling point, relative density, vapour pressure, surface tension, water solubility and partition coefficient. Moreover, many further physico-chemical tests are available as well including granulometry, flammability, viscosity etc and screening tests for thermal stability (e.g. explosive properties) using differential scanning calorimetry (DSC), if required.
|OECD 101||UV-VIS Absorption Spectra|
|OECD 102/A.1 ||Melting Point|
|OECD 103/A.2||Boiling Point|
|OECD 109/A.3||Relative Density|
|OECD 104/A.4||Vapour Pressure (static method / effusion method)|
|OECD 115/A.5||Surface Tension|
|OECD 105/A.6||Water Solubility|
|Partition Coefficient (n-octanol/water)|
|A.12||Flammability (contact with water)|
|A.13||Pyrophoric Properties of Solids and Liquids|
|A.15||Auto Ignition Temperature (liquids and gases)|
|A.16||Relative Self-Ignition Temperature for Solids|
|A.17||Oxidising Properties (solids)|
|A.21||Oxidising Properties (liquids)|
|OECD 112||Dissociation Constants in Water|
|OECD 113||Screening Test for Thermal Stability and Stability in Air|
|OECD 122||Determination of pH, Acidity and Alkalinity|
|OECD 29||Guidance Document on Transformation/Dissolution of Metals and Metal Compounds in Aqueous Media|
The UN methods are needed for purposes of the CLP Regulation (EC) No. 1272/2008 and the Global Harmonised System (GHS) for the Classification and Labelling as well as the Transport of Chemicals.
The goal of the GHS is to identify the intrinsic hazards found in substances and mixtures and to convey hazard information about these hazards. The criteria for hazard classification are harmonized and now form an integrated hazard communication system (ST/SG/AC.10/30/Rev.6)
|H.4||Heat accumulation storage test (Chapter 28.4.4)*|
|N.1||Test method for readily combustible solids (Chapter 33.2)*|
|N.2||Test method for pyrophoric solids (Chapter 33.3)*|
|N.3||Test method for pyrophoric liquids (Chapter 33.3)*|
|N.4||Test method for self-heating substances (Chapter 33.3)*|
|N.5||Test method for substances which in contact with water emit flammable gases (Chapter 33.4)*|
|O.1||Test for oxidizing solids (Chapter 34.4)*|
|O.2||Test for oxidizing liquids (Chapter 34.4)*|
|C.1||Metal Corrosivity (Chapter 37.4)*|
*UN Recommendations on the Transport of Dangerous Goods. Manual of Tests and Criteria (Fifth revised ed.), New York and Geneva: United Nations, 2009, ISBN 978-92-1-139135-0, ST/SG/AC.10/11/Rev.5
CIPAC's main objective is the standardization of methods (The CIPAC methods / Collaborative International Pesticides Analytical Council) for the analysis of pesticide products and physico-chemical tests for formulations. This standardization is achieved through the conduct of internationally recognized tests according to accepted procedures.
The CIPAC methods play an important role particularly for the registration and authorization of plant protection products. Depending on the formulation of the product, InterBioTox can perform the required method of analysis for your needs according to GLP compliance.
The analytical methods are mainly based on GC and HPLC techniques and are focused as well as to the physicochemical tests, which may consist of visual observations or of manipulations but, at present, are usually based on instrumental techniques.
|CIPAC MT 3||Specific gravity, density and weight per millilitre|
|CIPAC MT 15||Suspensibility of wettable powders in water|
|CIPAC MT 20||Viscosity|
|CIPAC MT 32||Determination of conductivity|
|CIPAC MT 33||Tap density|
|CIPAC MT 34||Dustability tests after tropical storage|
|CIPAC MT 36||Emulsion characteristics of emulsifiable concentrates|
|CIPAC MT 39||Stability of liquid formulations at 0°C|
|CIPAC MT 41||Dilution stability of herbicide aqueous solutions|
|CIPAC MT 44||Flow number|
|CIPAC MT 46||Accelerated storage procedure|
|CIPAC MT 47||Persistent foaming|
|CIPAC MT 53||Wettability|
|CIPAC MT 58||Dust content and apparent density of granular pesticide formulations|
|CIPAC MT 59||Sieve analysis|
|CIPAC MT 75||Determination of pH values|
|CIPAC MT 148||Pourability of suspension concentrates|
|CIPAC MT 159||Pour and tap bulk density of granular materials|
|CIPAC MT 160||Spontaneity of dispersion of suspension concentrates|
|CIPAC MT 161||Suspensibility of aqueous suspension concentrates|
|CIPAC MT 167||Wet sieving after dispersion of water dispersible granules|
|CIPAC MT 169||Tap density of water dispersible granules|
|CIPAC MT 172||Flowability of water dispersible granules after heat test under pressure|
|CIPAC MT 174||Dispersibility of water dispersible granules|
|CIPAC MT 179|
Dissolution degree and solution stability
|CIPAC MT 180||Dispersion stability of suspo-emulsions|
|CIPAC MT 184||Suspensibility of formulations forming suspensions on dilution with water|
|CIPAC MT 185||Wet sieve test|
|CIPAC MT 186||Bulk density|
|CIPAC MT 191||Acidity or alkalinity of formulations|
|Technical Monograph n°17 (2nd Edition)||Storage at ambient Temperature 2 years (at 20oC)|
Aerosol products are present in different industries including cosmetic, technical, household and many more. These products are subject to number of controls both at the pre-production, in-process and post-production stages.
FEA (European Aerosol Federation) has developed guidelines for aerosol testing to ensure a safe use. The following study could be applied by the laboratory of InterBioTox to Biocidal Products and Pesticides with spray applications
|FEA 644 E||Evaluation of aerosol spray patterns|
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