​Analytical Chemistry 

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​Analytical chemistry is a science-based discipline that deals with ways and methods for decomposition of substances and determining their composition resp. distribution. The procedure / methodology used to achieve this analysis is called chemical analysis.

The use of analytical chemistry is very extensive and has a wide application. It can be encountered in industry when evaluating raw materials, products, intermediates but also finished products, in quality control of products, operation control, production processes in chemical, pharmaceutical, biotechnology, plant protection, food industry etc.

Analytical Chemistry represents also a very important part within some toxicology, ecotoxicology, degradation studies resp. environmental fate studies. It quantitatively resp., qualitatively determines the testing items, their metabolites or degradation products, their distribution in various spectrum of environmental, human and other matrices e.g. water solutions, soil, sediment, blood, plasma, feed material (formulations). 


The analytical laboratories of InterBioTox offer a complex range of services to support your chemistry requirements and are qualified and competent to examine analytically a wide variety of substances and matrices within toxicological and ecotoxicological studies.

Our analytical staff is experienced and has a strong background supporting regulatory studies acquired over many years in the chemical, pharmaceutical, biocide, medical device, plant protection products, food industry etc..

InterBioTox offers our clients supporting GLP analysis for ecotoxicological, toxicological and physico-chemical studies, from the development of the analytical method to the validation and implementation. We can also assist you with the substance characterization in accordance with sameness studies under REACH as well as with the analysis of active substances in pesticide or biocide formulations.


Our GLP services are comprised:

  • Test Substance Identification (Sameness)
  • Development, Implementation and Validation of Analytical Methods
  • Verification of concentration, stability and homogeneity in vehicles, solvents and formulations
  • Revalidation or ILV Studies (Independent Laboratory Validation) for the identification and quantification of active substances in Plant Protection Products according to SANCO/3030/99 rev. 4
  • Analytical Measurements within Ecotoxicological, Toxicological and Physico-chemical Studies
  • Residue Studies of Formulations in Various Matrices
  • 5-Batch Analysis for the plant protection products (pesticides)
  • The shelf life stability studies in the 3 different zones

We use a broad spectrum of state-of-the-art analytical equipment within the chemical analysis and chromatography. 


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Analytical Chemistry

  • UV-VIS
  • FTIR
  • Liquid-Scintillation-Counter
  • ICP-OES
  • TOC
  • Titration

Chromatography

  • GC / FID, ECD, NPD
  • GC-MS / EI, Headspace
  • HPLC / UV, RI, FLD, ELSD, RAD
  • HPLC-MS / ESI, APCI
  • LC-MS / MS

Requirements for Substance Identification (Sameness)

Sufficient spectral data are needed to confirm the structure and composition of the chemical substance. Several spectroscopic and analytical methods can be suitable. It is the responsibility of the registrant to present appropriate data depending on several substance information. We provide you with the necessary analyses and data:

  • GPC

  • UV/VIS

  • IR

  • 1H-NMR/13C-NMR/solid NMR

  • Mass spectrum: GC/MS with Headspace and LC-MS or LC-MS/MS

  • GC/HPLC Chromatogram

  • ICP-OES
  • XRF
  • XRD
  • Titration
  • Water content (Gravimetric, Karl Fischer, Freeze Drying)

Analytical Requirements for Pesticides and Plant Protection Products

Interbiotox offers you a comprehensive GLP analytical service for your Pesticides and Plant Protection Products:

  • Development and Validation of Analytical Methods
    acc. to SANCO/3029/99C

  • Residue Studies
    acc. to SANCO/825/00  and 
    acc. to OECD 506: Stability of Pesticide Residues in Stored Commodities
  • Accelerated Storage Stability
    acc. to CIPAC MT 46  and 
    Stability of liquid formulations at 0°C acc. to CIPAC MT 39
  • Long Term Stability (Shelf Life Stability)
    acc. to Technical Monograph n°17, 2nd Edition, 2 years at ambient temperature
  • 5-Batch Analyses (Active Ingredient and Impurities)
    acc. to SANCO/3030/99
  • ILV Studies (Independent Laboratory Validation)
    acc. to SANCO/3030/99

Analytical  Requirements for Biocides

Interbiotox provides you a comprehensive GLP analytical service for your Biocidal products:

  • Chemical Equivalence Studies

  • 5-Batch Analysis (Active Ingredient and Impurities)

  • Residue Studies

  • Accelerated Storage, Low Temperature  and Long Term Stability

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